The aim of this Rapid Evidence Assessment (REA) was to conduct a review of the scientific evidence regarding whether occupational exposures to jet fuels and specified solvents of most relevance to the military were associated with risks to the reproductive health of women.

The aim of this Rapid Evidence Assessment (REA) was to conduct a literature review of adverse sexual and reproductive health outcomes in men from occupational exposure to specified solvents relevant to the Australian military.

The final report, Research into the Toxicological Effects of Chemicals used in the F-111 Deseal/Reseal (DSRS) Programs, was completed in 2005. The study was undertaken by the University of Sydney to examine the toxicological effects of chemicals used in the F-111 DSRS programs, in particular the chemical SR-51. The aims of the study were to examine the toxicological effect of SR-51 on memory loss in mice, the effect of temperature changes on the toxicity profile of SR-51 and whether SR-51 caused cancer through the process of DNA damage.

Results from the third study of mortality and cancer incidence among F-111 aircraft maintenance personnel, commissioned by the Australian Government Department of Veterans' Affairs, were released on 20 February 2009 by the Australian Institute of Health and Welfare (AIHW).

The report, Third study of mortality and cancer incidence in aircraft maintenance personnel: A continuing study of F-111 Deseal/Reseal personnel, is a follow-up study into mortality and cancer incidence in aircraft maintenance personnel involved in the F-111 aircraft Deseal/Reseal (DSRS) programs between 1977 and 1999. Findings from this study are consistent with the 2004 study. Findings indicate that although overall cancer incidence in men who were involved in DSRS programs was higher than the Australian male population, the numbers were too small to be statistically significant. Additionally, overall mortality was lower for DSRS personnel when compared with the Australian male population.

The AIHW believes that the small numbers make interpretation of these results inconclusive and recommends that the study be repeated in 2011 when more data will be available to improve certainty about the findings.

The report of the Fourth study of mortality and cancer incidence in aircraft maintenance personnel:

A continuing study of F-111 Deseal/Reseal personnel, was released on 17 October 2016 by the Australian Institute of Health and Welfare (AIHW). The broad purpose of this follow up MCIS study was to see if there was a higher rate of cancer or mortality among Royal Australian Air Force (RAAF) and civilian aircraft maintenance personnel involved with F-111 Deseal/Reseal (DSRS) between 1974 and 2000 compared to other RAAF personnel who were not involved.  

The key findings are broadly consistent with the previous studies taking into consideration the additional years of follow-up and differences in the datasets. The latest study added information from ‘Tier classifications’ to identify more personnel in the study group. 

Higher cancer incidence and lower mortality incidence among the F-111 DSRS group was found to be statistically significant due to the greater number of cases that have occurred over time.